KMID : 0882420070720030290
|
|
Korean Journal of Medicine 2007 Volume.72 No. 3 p.290 ~ p.297
|
|
The Relationship of epicardial adipose tissue to metabolic syndrome and cardiovascular risk factors.
|
|
Baik Seung-Hee
Ahn Sung-Gyun Choi Jung-Hyun Koh Bo-Ram Yoo Jun-Hwan Kang Soo-Jin Choi Byoung-Joo Choi So-Yeon Yoon Myeong-Ho Tahk Seung-Jea Shin Joon-Han
|
|
Abstract
|
|
|
Background: Increased adiposity is widely accepted as the main expression of obesity and an important risk factor for the development of cardiovascular and metabolic syndrome. The significance of epicardial adipose tissue (EAT), frequently observed during a transthoracic echocardiographic examination, is not well recognized. The purpose of this study was to investigate the relationship of EAT to metabolic syndrome and cardiovascular risk factors.
Methods: We collected clinical, biochemical, and anthropometric information from 289 consecutive and prospective patients (147 men; 59+/-11 years) who visited our hospital for a complaint of chest pain. EAT thickness was measured by transthoracic echocardiography on the free wall of the right ventricle in the parasternal long axis and short axis views at the base level during end-diastole.
Results: EAT thickness was significantly increased in 185 (64%) patients with metabolic syndrome as compared with patients without metabolic syndrome (4.3+/-2.5 mm vs. 3.6+/-2.8 mm, p=0.005). By a simple linear regression analysis, EAT was correlated to age (r=0.484, p<0.001), waist circumference (r=0.177, p=0.01), the level of HDL cholesterol (r=-0.182, p=0.001) and log CRP (r=0.268, p=0.012). Multivariate analysis showed that age and log CRP were the independent variables that correlated to EAT thickness.
Conclusion: These results suggest that echocardiographic EAT should be considered as a new useful imaging indicator of visceral adipose tissue related to metabolic syndrome and cardiovascular disease.
|
|
KEYWORD
|
|
Epicardial adipose tissue, Echocardiography, Metabolic syndrome X, Cardiobascular disease, Risk factors
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|